Prototype Novel Dosimeter for FLASH Radiotherapy

Tender description

Recent advancements in radiation therapy, particularly the emergence of UHDR or FLASH-RT (Ultra-High Dose Rate Radiotherapy), have introduced a new set of complexities. FLASH-RT involves the delivery of radiation at remarkably elevated dose rates, exceeding 40 Gy/s. This revolutionary approach has demonstrated the potential to spare healthy tissues while effectively treating cancerous cells. It offers the promise of reduced side effects, shorter treatment times, and greater access to therapy. Unlike traditional ionisation chambers used in radiation dosimetry, the Transmission Calorimeter does not rely on ionization processes. Instead, it exploits the rise in temperature induced by absorption of the radiation beam. By accurately measuring this temperature increase, the Transmission Calorimeter provides a direct method for quantifying the radiation dose delivered to a target area. The Transmission Calorimeter system consists of two forms of device that need to be designed, manufactured, and assembled. These are: a. Electronic Readout Box: This box contains four DC Wheatstone Bridge circuits, each fed by a voltage regulator. It has panel mounted connectors to facilitate connection to the thermistor networks located within the Transmission Calorimeter and to enable monitoring of the “Bridge Out of Balance” Voltages, measured using external voltmeters and integrated Analogue to Digital Converters (ADCs). b. Radiation Sensor: This consists of two printed circuit boards (PCBs) and serves as the primary platform for thermal measurements. It is composed of two modules, the “active” and “compensating” areas. The Radiation Sensor will connect to the Electronic Readout Box. Several different sizes of Radiation Sensors are requested as part of this procurement process.