Supply & Delivery of Fomepizole

Tender description

This procurement is for the supply and delivery of the medication Fomepizole to locations in India and Bangladesh as part of the Centre for Cardiovascular Sciences’ project; NIHR RIGHT4: Preventing Deaths from Acute Poisoning in Low-and Middle-Income Countries (LMIC) - Work Package 1: Methanol This procurement is for the supply and delivery of the medication Fomepizole to locations in India and Bangladesh as part of the Centre for Cardiovascular Sciences’ project; NIHR RIGHT4: Preventing Deaths from Acute Poisoning in Low-and Middle-Income Countries (LMIC) - Work Package 1: Methanol; https://www.ed.ac.uk/cardiovascular-science/nihr-acute-poisoning Every year, thousands of people are poisoned by methanol, often in outbreaks affecting the poorest in society. Effective treatment is possible by blocking the metabolism of methanol to formate by inhibiting alcohol dehydrogenase with fomepizole or ethanol. However, such treatment can only follow early diagnosis of methanol poisoning, ideally within 12-24 hours. Unfortunately, diagnosis is difficult because methanol poisoning is a great imitator, resembling many medical conditions. Diagnosis has previously been complex, expensive, and slow, requiring measurement of blood methanol concentrations in a laboratory. There is therefore an urgent need to develop new forms of early diagnosis.