Supply of an Automated Patch Clamp for high throughput ion channel physiology

Tender description

A fully automated patch clamp system capable of multiple recording mode with the capacity to record from a minimum of 4 cells and expandable to 8 cells simultaneously. A fully automated patch clamp system that is robot controlled for cell & drug delivery to the experimental environment minimising the potential for human error. The system should be built on best in class electrophysiology amplifiers. The system must be able to allow Liquid junction potential correct and access to all common modes of Patch clamp recording (Cell attached, Whole cell, Current-Clamp, Inside-out and outside-out).The system should have built in filtering options from 10-100kHz at least. The system should allow for low frequency voltage clamp and have a selection of current clamp scaling options. Lot 1: General Requirements  A fully automated patch clamp system capable of multiple recording mode with the capacity to record from a minimum of 4 cells and expandable to 8 cells simultaneously.  A fully automated patch clamp system that is robot controlled for cell and drug delivery to the experimental environment minimising the potential for human error.  The system should be built on best in class electrophysiology amplifiers.  The software environment must be easy to use, flexible, adaptable and familiar.  The system must be self-contained without the requirement for additional installations either to the building or additional equipment i.e. no requirement for vacuum lines to be installed in the building or additional standalone vacuum equipment. Specification Requirement  The system must be able to allow Liquid junction potential correct and access to all common modes of Patch clamp recording (Cell attached, Whole cell, Current-Clamp, Inside-out and outside-out).  The system should have built in filtering options from 10-100kHz at least. The system should allow for low frequency voltage clamp and have a selection of current clamp scaling options.