Screening for spinal muscular atrophy (SMA)-Scoping of Work

Tender description

Scoping work for a decision analytic model and cost effectiveness evaluation of new-born screening for Spinal Muscular Atrophy (SMA). Therefore, the service is for the provision of a rapid review of the literature and for a plan to prepare for a future modelling study with clinical and cost effectiveness outcomes. It is not a screening pilot or an evaluation of one. Lot 1: Scoping work for a decision analytic model and cost effectiveness evaluation of new-born screening for Spinal Muscular Atrophy (SMA). Therefore, the service is for the provision of a rapid review of the literature and for a plan to prepare for a future modelling study with clinical and cost effectiveness outcomes. It is not a screening pilot or an evaluation of one.<br/>The purpose of this work is to prepare for a modelling study by:<br/><br/>• Objective 1: Conducting a review of available decision analytic modelling studies and cost effectiveness evaluations which address new-born screening for SMA in the era of novel treatments <br/>• Objective 2: Developing an evidence map of published studies and evaluations of PCR based screening and treatment in presymptomatic SMA <br/>• Objective 3: Proposing a plan for a modelling study with clinical and cost effectiveness outcomes <br/><br/>Estimated contract value (including extensions): £90,000 excluding VAT (£108,000 including VAT)<br/><br/>The opportunity will be available on the DHSC Atamis eTendering System. Select this link to access and register your organisation to the Atamis system https://health-family.force.com/s/Welcome, if you have not already done so.<br/>To find this opportunity in the eTendering system, select “Find Opportunities” and then search by project number or title. Once you have found the Opportunity, press the ‘Register Interest’ button to register your interest. This will make the project to appear on ‘My proposals and quotes’. From there you can review documents, send clarification messages, submit the response, or decline to respond, if you decide not to participate in the opportunity. For full details on the instruction to tender and terms of participations please refer to the Invitation to Tender document.