Expansion of G3Lab Bioprocess Controllers, Delta-V and Bioreactor Capability

Tender description

NIBRT currently has as part of its Analytics & Characterisation laboratory, 2 G3Lab controllers, one with a 7-litre glass bioreactor and one with a 3-litre glass bioreactor, acquired from Finesse in 2017, which is now part of ThermoFisher Scientific. The company now wishes to award a contract to expand the platform into an operational 7-litre four pack and to acquire an additional 7-litre vessel, and controller together with an upgrade to the TruBio Delta-V platform to allow for additional hardware capacity. The purpose of this expansion is to support a growing volume of work in advanced process related research. Lot 1: • Finesse bioreactors produce biotherapeutics in a controlled and sterile environment. • The mass flow controllers (MFCs) built into the G3Lab controllers allow for accurate control over the flow rate of gases entering the vessels which can have an impact on the characteristics of the product being formed. • This control is managed through the Delta-V software. • Aside from controlling the flow rate of gases the Delta-V software is capable of monitoring important variables within the vessel such as temperature, pH and gas concentration over time. It is important that these parameters are controlled and monitored carefully as they can have an impact on product characteristics. The signals for these parameters are sent from probes inserted into the bioreactor, attached to the G3Lab controllers and represented within Delta-V.