Equipment including single use bioreactors, biosealers, biowelders, benchtop controllers for stirred and rocking motion systems plus Single Use Centrifugal systems for the use in the manufacture of gene therapy drugs/treatment for research and development, education/teaching and training

Tender description

The University of Sheffield (UoS) is establishing a new 'Gene Therapy Innovation Manufacturing Centre' (GTIMC) to advance scientific discoveries into life-changing treatments for patients with life threatening diseases. The Sheffield GTIMC will be one of three cutting edge hubs in the UK dedicated to advancing the clinical development of new genetic treatments. This facility is due to open in the Summer of 2022 and further details can be found at the following link:- https://www.sheffield.ac.uk/news/new-gene-therapy-innovation-centre-advance-scientific-discoveries-life-changing-treatments The UoS requires various bioreactors and complimentary/integrated equipment (sealer, welder etc), in order to undertake this co-ordinated work in parallel to 2 other UK sites (NHS Blood and Transplant (Bristol) and Kings College London working on identical methods and processes. To ensure the consistency of the science and comparability of the results, the same equipment needs to be purchased as the other two facilities. Lot 1: In order to assist with the tech transfer from Catapult the following items are being purchased are to be purchased asap: 1 x Sartorius Biowelder 1 x Sartorius Biosealer 1 x Sartorius BIOSTAT® RM 20 / 50 (BIOSTAT® B - perfusion ready) 1 x Sartorius Twin UniVessel 2 L STR + BIOSTAT® B Between 2022 and 2027 the following items may be purchased:- 2 x Sartorius Biowelder 2 x Sartorius Biosealer 2 x Sartorius BIOSTAT® RM 20 / 50 (BIOSTAT® B - perfusion ready) 2 x Sartorius Twin UniVessel 2 L STR + BIOSTAT® B 3 x Sartorius Biostat STR 50 3 x Sartorius kSep The above equipment will be used to furnish one research and development lab and two clean rooms. Installation, commissioning, consumables, training and annual support/maintenance/calibration will be incorporated for between 3 and 5 years as part of the purchase. Additional information: Regulation 32 of PCR 2015 is being applied as in 32. (2) (b) (ii) and 32. (5) (a). No contract will be entered into until after a 10 calendar day period from the submission of the VEAT notice date. As of 27/07/2022 The University of Sheffield has placed orders for the following equipment:- a) 1 x Sartorius Biowelder and 1 x Sartorius Biosealer b) 1 x Sartorius BIOSTAT® RM 20 / 50 (BIOSTAT® B - perfusion ready) and 1 x Sartorius Twin UniVessel 2 L STR + BIOSTAT® B c) 1 x Sartorius Biostat STR 50