UKRI-1682 Mass Photometer

Tender description

Supply of Mass photometer and maintenance service: It derives molecular mass not indirectly from a measurement of the hydrodynamic radius (e.g. SEC or DLS) but from light scattered by single molecules, making it uniquely suited to differentiate between particles of similar size but different mass (e.g. loaded vs. unloaded gene delivery particles). As mass photometry measures the mass of each molecule individually it is uniquely suited to inform about complex samples and processes including sub-populations lost in ensemble measurements (e.g. SPR, BLI or DLS). The measurements can be done directly in solution, on minimal sample amounts and in a variety of buffer conditions. Lot 1: Supply of Mass photometer and maintenance service: It derives molecular mass not indirectly from a measurement of the hydrodynamic radius (e.g. SEC or DLS) but from light scattered by single molecules, making it uniquely suited to differentiate between particles of similar size but different mass (e.g. loaded vs. unloaded gene delivery particles). As mass photometry measures the mass of each molecule individually it is uniquely suited to inform about complex samples and processes including sub-populations lost in ensemble measurements (e.g. SPR, BLI or DLS). The measurements can be done directly in solution, on minimal sample amounts and in a variety of buffer conditions.