Provision of Protein G Sepharose and consumables

Tender description

Public Health England (PHE) is seeking to purchase affinity chromatography resin to perform the depletion of IgM from human plasma at the 500ml-1L litre scale. This product is for the Pathogen Immunology Group within National Infection Service (NIS) Laboratories research department. PHE requires the IgM affinity resin to support the chromatography process developed in house. The requirement must meet the following mandatory specifications for IgM affinity resin - Must be available in 500ml batches. - Must have proven track record for the depletion of IgM from human plasma at the 500ml scale. - Must provide consistent IgM depletion without activation of either the Complement cascade or the coagulation pathway at the 500ml scale. - Must withstand harsh sanitisation regimes without any loss of efficacy with heavy, sustained use. If you feel that you can meet the above requirements or would like more information, then please contact Aysel Sarzosa Aysel.Sarzosa@phe.gov.uk.