STRATA Clinical Trial

Tender description

Anxiety is common in adults with a diagnosis of autism and can be more disabling than the core features of autism. Medications for anxiety are often prescribed for adults with autism but their effectiveness or side effects in this population are not well known. Aims: i) to determine the effectiveness of the Selective Serotonin Reuptake Inhibitor (SSRI) sertraline in reducing symptoms of anxiety and improving quality of life in adults with a diagnosis of autism compared with placebo and quantify its adverse effects; ii) to determine its cost effectiveness; iii) to explore patients' views and experiences of taking study medication and identify reasons for completing/not completing the study.