SUPPLY AND DELIVERY OF A POWDER PARTICLE SIZE ANALYSER

Tender description

As part of the Bernal Project, UL is establishing a National Pharmaceutical Processing Suite which will further enhance the capacity and capabilities of the Solid State Pharmaceutical Cluster (SSPC) in support of the Pharmaceutical Sector in Ireland. Included in this suite will be a Powder Extrusion Suite for the development of novel pharmaceutical solid dosage formulations. The suite will comprise of pharmaceutical extrusion equipment with integral Process Analytical Technology, providing the basis for an advanced academic and pharmaceutical manufacturing capability in Ireland. The state-of-the-art features, which are nationally unique, include the provision of real-time analysis of particle size distribution from continuous processes. An essential aspect of this proposal is that the equipment within the suite has been specifically indentified to allow detailed investigations of pharmaceutical powder processes (e.g., extrusion, granulation, blending, drying) in bench scale systems, which can be used to investigate process parameters of small volume, novel formulations. This particle size analytical capability along with appropriate software and storage package, to monitor and record the particle size and shape of a powder mass, is seen as essential by industry. Moreover, the equipment will be available for all academic and industry users in SSPC. The main feature of the system will be applicability for in-line monitoring, control and optimisation of powder processes.